Ovaprim® Syndel

Description

Usage

Induce spawning via stimulate ovulation and spermiation in sexually mature fish.
Dose: General dose 0.5 ml per kilograms of fish

Net Contents:

10 ml
Salmon Gonadotropin Releasing Hormone (sGnRHa) with Domperidone
injection.

Each ml contains:

20 mcg sGnRHa
10 mcg Domperidone

Storage:

store below 25°C

Warning:

Not for use in humans. Keep medicine out reach of children.

Description

Ovaprim® is a liquid peptide preparation that contains an analog of salmon gonadotropin releasing hormone (sGnRHa) and a brain neurotransmitter (dopamine) inhibitor. The sGnRHa in Ovaprim® elicits the release of stored gonadotropins from the pituitary. The dopamine inhibitor (Domperidone) serves to remove other inhibition of GnRH release. Release of stored pituitary gonadotropins may aid spawning by stimulating ovulation and spermiation in sexually mature fish.

Directions for use

Ovaprim® is packaged ready for use in liquid form. Precise amounts for individual injections should be withdrawn directly from bottle into a syringe.

Cleanliness

Syringes/needles should be sterile prior to use.

Loading

Withdraw only enough solution from bottle as will be required for the weight of the fish. With the needle pointed upward and directed away from your face, squeeze the syringe gently to expel any trapped air.

Injection

Hold the fish firmly and insert the needle into abdominal cavity/ belly between the pelvic fin and the vent or into the muscle on either side of the dorsal fin. For intra-abdominal injection in smaller species, it may be helpful to secure the fish on a soft wet surface such as a sponge, and to place the fish on its side and inject into rear abdominal cavity to avoid contact with internal organs. Inject Ovaprim® carefully. After injection, gently place the fish into a container of clean aerated water.

Use of a needle guard to limit the penetration of the needle into the fish may be helpful.

Sedation for handling and recovery

If necessary, sedate broodstock prior to Ovaprim® injection.

DOSE

A general dose of Ovaprim® is 0.5 ml per kilogram of bodyweight. The dose may vary among fish species and physiological state of individual animals. Environment and temperature also play a significant role in the reproductive process and may affect dose and timing.

• Single dose of Ovaprim® is only effective in fish that are within or near their natural spawning season.
• Split dose of Ovaprim® may be needed for fish that are without their natural spawning season. For split dosing, a loading dose of 10% of the total dose should be injected, followed by injection of the remaining 90% of the total dose at least 6 hours later.

Effect

In warm water species, ovulation may occur in as little as 4 hours post treatment, so fish should monitor accordingly. it is important to note that the interval between treatment and the onset of ovulation is variable between species and temperature. Treated fish should be disturbed as little as possible to reduce stress during final maturation. Males may respond in shorter periods of time than females of the same species.

Signs of Ovulation/Spermiation

• Noticeable swelling and “softening” of the abdomen.
• Presence of eggs in the water.
• The ability to easily express eggs from the female and milt from males
• When sexes are held together in the same tank, onset of spawning behavior (e.g., males “chasing” females).

Suggested Dosage

The dose is calculated based on the weight of the fish.
(Fish Weight) x (Ovaprim® Dosage) = Amount of injection

Suggested Ovaprim® Dosage=0.5 ml/kg of fish